Document Details

Document Type : Thesis 
Document Title :
Synthesis and antimicrobial activity of novel thiazolidinone derivatives
التشييد والنشاط المضاد للميكروبات لمشتقات ثيازوليدينون الجديدة
 
Subject : Faculty of Science 
Document Language : Arabic 
Abstract : The aim of this proposal is to synthesize and characterize a series of new novel thiazolidinone derivatives and study their biological activities. These compounds are proposed to be synthesized by condensation of different aldehydes with thiosemicarbazide, and cyclization with chloroacetic acid or ethyl bromoacetate in presence of sodium acetate to offer the new thiazolidinone derivatives. To fully elucidate the chemical structure of all newly synthesized compounds, elemental and spectral analyses such as melting point, FT-IR, and multinuclear NMR (1H and 13C) spectroscopy will be performed. The biological activity of the newly synthesized compounds will be investigated, such as antibacterial and antifungal activities. Our new series of heterocyclic compounds are anticipated to show great therapeutic properties as it contains thiazolidinone derivatives, attracting the attention of medicinal chemists to synthesize many chemotherapeutic agents. Keywords: (synthesis, 4-thiazolidinone, thiosemicarbazone, biological activity, antimicrobial activity) 
Supervisor : Dr. Zahra Mohammad Alamshany 
Thesis Type : Master Thesis 
Publishing Year : 1445 AH
2023 AD 
Added Date : Sunday, October 15, 2023 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
وفاء عويضه السلميAlsulami, Wafa OwaydhahResearcherMaster 

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